Baglo, Yan; Gabrielsen, Mari; Sylte, Ingebrigt; Gederaas, Odrun Arna (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Photodynamic therapy (PDT) is a safe and effective method currently used in the treatment of skin cancer. In ALA-based PDT, 5-aminolevulinic acid (ALA), or ALA esters, are used as pro-drugs to induce the formation of the potent photosensitizer protoporphyrin IX (PpIX). Activation of PpIX by light causes the formation of reactive oxygen species (ROS) and toxic
responses. Studies have indicated that ...